As long as you have information being written into or being read from the database, VirusScan is going to scan it. That's what it is supposed to do. Now you can exclude your database from being scanned and VS won't scan it. But unless you exclude it, it will be scanned.
On our SQL servers, we disable 1) backup* (read/write) & 2) mssql* (read/write) from VS7 on-access scanning. This was based on feedback from our DBAs & cured any performance issues.
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