This is Windows XP SP3. I have encountered an extremely nasty virus/spyware situation and everything I have tried has produced some results but not enough to straighten out the machine. The malware/virus occurred under a user with administrative rights. This user does alow for a boot up but the system is not very functional. Most icons render an "Application Not Found" message or a "Select the Program to Opwn This with" window with a list of choices. There is the standard administrative login that, while not perfect, does allow me to perform some analysis and take some corrective measures. From that login I have run MalwareBytes which caught close to 80 things, then I ran SuperAntiSpyware which caught about another 15, then I ran Spyware terminator which caught another 4 and then I ran an Avast scan which also caught four items. After this I tried unsuccessfully to implement several previous restore points but none of them ran successfully. The restore point I created today before trying to run the older ones did restore properly. I ran Combo Fix which caught a RootKit and rebooted and then finished upon reboot. I then rebooted and logged in under the other login but all the corruption characteristics are still there. I tried to download ComboFix and run from this login but the icon functions like all the other corrupt icons, producing a "Select the Program to Open this with" window. I am looking for suggestions, ideas, assistance before I just install a new drive, lay down a fresh install, grab the files I need off the old drive, and move on. I would like to fix this if at all possible. Thanks much for any assistance!!!