This should return just the numeric:
SELECT SUBSTRING('Filler Order ID: <10190968MMDSCR> Filler Facility ID: <RAD>',CHARINDEX('<','Filler Order ID: <10190968MMDSCR> Filler Facility ID: <RAD>')+1,CHARINDEX('>','Filler Order ID: <10190968MMDSCR> Filler Facility ID: <RAD>')-CHARINDEX('<','Filler Order ID: <10190968MMDSCR> Filler Facility ID: <RAD>')-1)
You obviously need to replace the:
'Filler Order ID: <10190968MMDSCR> Filler Facility ID: <RAD>'
with the actual field name throughout the statement and drop the SELECT from the start that was just for testing . it should look more like:
SELECT Field1, Field2, SUBSTRING(Field3,CHARINDEX('<',Field3)+1,CHARINDEX('>',Field3)-CHARINDEX('<',Field3)-1) AS Field3ID
FROM TABLE1
Hope this helps