It should also be noted that AIX uses all otherwise unused physical memory for file page caching, only releasing the memory when needed to keep the free list above minfree. So once a system has accessed (physical memory - (minfree + program allocated memory)) different file pages, the physical memory will remain fully used until a reboot.
In topas, these file cache pages show up as "% Noncomp" under memory.
Rod Knowlton
IBM Certified Advanced Technical Expert pSeries and AIX 5L