Try restarting the server in safe mode, DS restore mode if it's a DC, which I hope it's not.
If that fails, what about the recovery console.
Then move those logfiles out of the way, don't delete them if you can help it. Then do a backup.
We had a client that had 14GB of log files, just because the idiot who configured the backup software thought it was a good idea to backup the M: drive as well. Yes It was me!
One point on this, stay well away from the M drive, no backup, and no virus scan.
Hope it helps,
One last point, has everyone heard of MS Critical Support, you can't use it on your own stuff, but when it comes to customers machines, and you get there and can't login etc. it might just save the day, and it's free.
Chris
Chris Styles
NT4/2000 MCSE