Running exe files from a browser is a bit of a security risk so it's generally not advised. However, if you use something like :
<script type="text/javascript" language="JavaScript">
function runCmd() {
var oShell = new ActiveXObject("Shell.Application"

;
var cmdToRun = "C:\winnt\Notepad.exe";
oShell.ShellExecute(cmdToRun,"","","open","1"

;
}
</script>
and muck about with the permissions, you might be able to do it (I think the browser has to be able to interact with the desktop or something).
Other options are you could try ASPExec (
but I think that is just for running apps on the web server.
As for running Access though, you should find that Access has a nice "Create data access page" function that converts the tables to ASP code for you which might be worth a try.