I have a similar problem as thread229-853644 where the solution was to fix the properties in the jpg. I did that and tried the Ctrl-Alt-Shft thing too. I pressed them in time and got the message to delete the settings. When I click yes, I still get the "file locked" message. If it is the scratch disk setting problem, I can't get PS open to change it. This problem started when I was opening a locked jpg from a relative. (Now none of my previous pics will open either). Any other ideas other than these that are already listed in the forums? Thanks for any help.