It will work, but is very unsupported!
I have a site running EntMan/Ops, Teleworker and ME on ONE box! The box is a Quad Xeon with 4 gigs of ram, they went all out on the host machine. It runs Win 2003 as the host OS with 4 nics in it. Using VMWare server (or whatever they call it now). The host OS has no apps installed.
Nic 2 is dedicated to Entman/Ops, 3 is TW, 4 is ME.
In VMWare you specify what nic each virtual session will use. It was a bear to set up, and product support will not help at all. The customer is very VMWare savey, all of their servers run in a virtual environment for ease of maintenance. Now, if that box ever goes down they obviously lose all Mitel apps, but it runs Raid 5 with redundant power supplys and 4 processors, so it's quite a robust machine.
They can move all apps to a new machine in about 20 minutes flat, so recovery is quite easy. They love it, and I hate it.
