What are you trying to accomplish? A TTX file is a data description file, which is useful in designing a report, but it does not contain any data, so it is not actually a data source.
I'm not sure what you mean by <<link the TTX file in design time at run-time>> Are you using the RDC? I have no experience with that integration object. All I know is that you can use a TTX file in the CR report designer to develop a report layout, but you must then assign a real data source, e.g. from a VB or Web App, to run the report. That's when and how you use the SetDataSource method. I repeat, a ttx file is NOT a data source, persistent or otherwise. It is a way to design a report without using a data source.
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