datadan's point about reliable builds is a good one. You really just need to go by your own experience with your servers.
We have SQL running on an NT4 server that has a very light load. I rebooted it last week after about 18 months of trouble free operation.
We have a Domino Mail server on an NT4 box that gets rebooted maybe once a year.
We have several Domino web severs running on NT4 and Win2K boxes that get rebooted 3 or 4 times a month. These are usually caused by some problem with the Domino and MQSeries applications however. No telling how long they would run without those errors.
We do not schedule reboots just for the sake of rebooting.
I try to reboot weekly since I notice a degration in network performance. This is a Backoffice 4.5 Server running a full gambit of software: backup, virus checking, etc.
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