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source: WikipediaAlone, silica gel is non-toxic, non-flammable and chemically unreactive. However, some of the beads may be doped with a moisture indicator, such as cobalt(II) chloride, which is toxic and may be carcinogenic. Cobalt (II) chloride is deep blue when dry (anhydrous) and pink when moist (hydrated).
Crystalline silica dust can cause silicosis but synthetic amorphous silica gel is non-friable, and so does not cause silicosis.