I agree with Braddds, I will stick with AVG and Kerio.
I used CA InoculateIT Personal edition when it was free and when CA ceased supporting it, switched to AVG.
With regards to InoculateIT PE, I was particularly impressed with the low memory and cpu usage footprint, but the user interface was dire and the protection didn't seem too strong as far as I was concerned. It seemed to me to be more of a one click scanner rather than resident background protection, but never got a virus so couldn't prove it one way or the other. I was on a student budget at the time so couldn't afford anything better.
Obviously this could have changed since the rewrite and release, but I was not particularly impressed with it and will stick with AVG.
John