I ran out of ideas, so hopefully someone might have run into this problem. Windows 2000 Professional computer was having issues -- whenever you would click on My Computer, OR Internet Explorer it would give the error message "explorer.exe has generated error messages..." and the same error message with IE (with the exception of explorer.exe replaced with iexplore.exe). Did a virus scan, installed service packs, tried installing ie 6... Here is the kicker, if I start-run-c:\winnt\explorer.exe I can click on My Computer all day long with no errors. (Obviously when the computer is rebooted My Computer starts to have a problem again.) Internet Explorer still causes errors - but, I'm looking to take one issue at a time!