See if the problematic CD will run in Safe mode.
But you'll have to do the following in order to access the CD-ROM drive in that mode:
-Copy both the oakcdrom.sys file(located in C:\Windows\Command\EBD) and the mscdex.exe file
(located in C:\Windows\Command) to the C:\ root folder.
-Go to Start/Run, type sysedit in the box, click OK, type LH c:\mscdex.exe /D:IDECD1 in the autoexec.bat window, close the autoexec.bat window, type device=c:\oakcdrom.sys /D:IDECD1 in the config.sys window, and close System Config. Editor.
-Restart the computer, press and hold the CTRL key, select 'Command prompt only' from the startup menu, press Enter, at the C:\> prompt type win/d:m, and press Enter to start Safe mode.
You will now be able to use your CD-ROM drive in Safe mode.
If it works in Safe mode, then go to Start/Run, type msconfig, click OK/Startup, and uncheck any boxes that have cafe95 or cafe95.exe in them.