Design questions/suggestions rather than code:
MUST all Acrobat apps be closed automatically? If not, you can search for "Acrobat" in the title as suggested in prior posts and prompt the user to close each app containing the string.
It is probably best to tell the user what you are doing anyway instead of just trying to auto-kill programs (for you installer/updater?)
You could send a terminate message to each app and let it handle the closing message normally (i.e. prompt to save if document changed, etc.). However, suppose someone has a slow connection or had a hard time finding a .PDF file, yet forgot to explicitly save a local copy. The .PDF will be read-only and will probably close without prompting the user. Some users will know how to retrieve the file from their temp internet folders (or a link back to the file), but many will not. They are the ones that will be irritated the most at having their computer guess (incorrectly) their highest priority(ies).
I would say:
1) Prompt the user before any app search "All Acrobat applications must be closed before this operation can complete. Please save your work and then click Continue". Give THEM a chance to close gracefully.
2) Now search for apps with "Acrobat" in the title and send a Terminate/closing message to the app and let it handle the message normally.
Now if the user loses any data it is their own damn fault for not paying attention.