I've searched the forum and haven't seen anything similar to this. I have a BES 4.0 and 5 users. We all use Outlook 2003 with our 5.5 Exchange Server. I can set a user up on the BES and do the wireless activation no problem. Email works great. I run into problems when I try to sync my Blackberry with the Desktop Manager. We don't keep contacts, tasks, etc. on the Exchange Server, we keep them in our local .PST file on our laptops. On the Blackberry, in the Options section of Address Book, Calendar, Tasks, and MemoPad I change the Wireless Synchronization to NO. I then go into Desktop Manager and go to Configure PIM where I point all 4 items to the local .PST file. After I synchronize with the handheld, I can receive emails, but I can't send (or reply) to emails. Anybody ever run into this??