I have seen similar symptoms before, and I seem to remember it was caused by a virus.
If memory serves me correctly, Stinger (http://vil.nai.com/vil/stinger) found and removed the virus but I then had to repair Windows installation. (Boot from XP CD, press "enter" to set up windows then press...
Re: the laptop issue
Do you deploy a wallpaper by group policy? If so the options will be greyed out when you log into domain but will be available again if you log on to local machine with admin account.
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