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Registry VirtualizationI'd love to know where you found "Microsoft site suggests the use of .INI files as a replacement", as that's news to me.
While this doesn't rule out HKCU (and actually mentions it indirectly as a valid place for storing settings) there have been plenty of suggestions that developers move to ini or config files instead. Note that per-computer settings are clearly meant to live outside the registry entirely though.Virtualization is intended only to provide compatibility for existing applications. Applications designed for Windows Vista should not write to sensitive system areas, nor should they rely on virtualization to remedy any problems. When updating existing code to run on Windows Vista, developers should ensure that applications only store data in per-user locations or in computer locations within %alluserprofile% that properly use an access control list (ACL).