We are running Exchange Server 5.5 and Outlook 2000 and 98. All users can send internal mail but 90% cannot send Internet mail from their mailbox but can if they setup Personal folders and send from there. We use a POP3 server for our internet mail at another site, this is working fine and as I said some users at our site have no problem. Also if a user with the problem sets up their profile on one of the working machines their mail works fine from the mailbox, likewise if a working user sets up on a non-working machine their mail stops working. I have been looking at this all weekend so any help would be appreciated.