Yup... bad entry in RUN key. It refers to symante~1, and you probably have several folders that start with the name symantec... so really, it's not a bad entry... it's just a short filename conflict, and as a result it opens up a folder rather than an executable... sorta like creating a RUN entry that has a value C:\windows, which will open the Windows folder upon login.
I recommend locating VPTRAY.EXE and then put a long path name in the run key:
OLD situation:
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Run\vptray = C:\PROGRA~1\SYMANT~1\SYMANT~2\VPTray.exe
NEW situation:
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\Run\vptray = C:\Program Files\Symantec Client Security\Symantec Antivirus\vptray.exe
(please double check the path before you proceed.)
After implementing the registry change, just logoff and relogon to see whether you were successful. Hope that fixes it for you.