You can't - simple as that. Acrobat does not support this funtionality. Every time you click Save or Save As, the folder in which the file to be saved resides will be the one which is selected as default. Ahhhhh, I see you have a machine that goes Bing!
Just a thought - would you want to do this just on your own machine? If so it would be possible to write a batch sequence that will perform a SaveAs operation to a specified location/filename. Ahhhhh, I see you have a machine that goes Bing!
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