I have a user who is having problems accessing his work PC using RDP via a VPN connection from home. Everything was fine until a few weeks ago. We had a situation where some users where not able to access their email at the work place after some changes to our Group Policy to disable using a Proxy for Internet Explorer. Did a GPUpate /force on the Servers and Workstations and everything seemed to work ok. After that a certain user could no longer access his work PC from home using RDP via VPN. I tried as well and could not. I get the message "This computer can not connect to the remote computer". If I try to ping by IP or name the request times out. If I ping by name you see the correct IP address in the ping message. I can RDP to other PCs and Servers with no problem. I can RDP to the PC at the work place ok. I verifeid his settings against other PCs and they match. Rdp is enabled, Allow logon through term. service is enabled, Firewall off, and he is a local admin as well as a Remote Desktop user member. The weird thing is, it seems to work during the day. If I am sitting in front of his PC and I use my Verizon wireless card on my laptop I can get in but when I try it in the evening to check, I have same problem. I did a search for VPN and RDP problems on TEK-TIPS and tried some of the solutions suggested there but non worked although I did not look at every post. We use a Cisco VPN client and the VPN Server is a Pix 515E. I can connect to other PCs, Email and shares ok. If I do a tracert it makes it to the first hop which is our core switch (Cisco 3550) and timeout after that(the next hop would be the PC) . I can ping other devices ok. Any suggestions would be much appreciated.