I recently got a new computer with a MS Wireless Desktop and the scroll wheel on my mouse doesn't work. I have a Wireless Optical Mouse 2.0A, Wireless Comfort Keyboard 1.0A, Wireless Optical Desktop Receiver 3.0A and I have installed IntelliPoint 5.0 and IntelliType 5.2 on Windows XP Pro SP2 + all updates. I've tried it both with USB and the PS/2 adapter. I took my old MS wired optical mouse and the scroll wheel works fine.