Do you want to start it from within VB? If not open ACCESS, go to the File menu, > Get External Data > Import. If you want to open the file from within vb then access the table,this should get you started:
Dim cnConn as adodb.connection
dim sLine as String
Dim iFileNum as integer
Dim sSQL as string
dim vOne,vTwo,vThree as string
set cnConn = createobject("ADOdb.connection"

iFileNum = Freefile
Open "C:\yourfilepath" For Input As #iFileNum
cnConn.connectionstring = "Driver={Microsoft Access Driver (*.mdb)};Dbq="C:\YourPath";Uid=Admin;Pwd=;"
cnconn.open
Do Until EOF(iFileHeader)
Line Input #iFilenum, sLine
'set the variables to your file structure
vOne = Mid$(slIne,2,4)
'vtwo = something
'vthree = something
ssQL = "INSERT INTO TABLE(F1,F2F3,)VALUES('" & vOne & "' & "," & '" & vTwo & "' & "," & '" vThree & "' & "

"
cnConn.execute ssql
Loop