Not enough information.
Building a filesystem structure for a database is 50% science and 50% black art.
If you have a large database with transactions, logging, indexing as well as your raw data and swap space, you will probably do better leaving your disks as single spidles (or mirrors of single spindles) and so your log/transaction/swap/index/data writes are effectively independent. You may find that striping all your disks together then carving them up with a logical volume manager will have a serious performance hit due to the seek times of the disk heads. This is especially true if you are dealing with a large number of small writes.
If you have a simple database structure that does large, sequencial writes, a mirrored stripe (or preferable a striped mirror) may be your best best.