IPSEC VPN with CIsco PIX and/or Citrix SSL?

[rerhart]

I need to create very secure connections from multiple client sites in the US to my site in MN via the Internet with Citrix clients. What would be considered "secure enough" or "most secure":

1. Cisco IPSEC VPN tunnels from routers to a central PIX.
2. SSL connections using SSL Web portal and Citrix SSL 128-bit client connection.
3. Both.

Thx!