parker:
Click and drag a brush from the palette to the artboard. An expanded version of the brush will appear on the artboard wherever you drop the brush. The expanded brush will be grouped.
For the next step, use the group select tool (white arrow with +).
Look for duplicate versions of objects (when the brush is created/expanded, in some scenarios strokes and fills become separate objects) you can reduce this object redundancy by eliminating one and applying the appearance to the leftover one. Fewer objects, less memory.
Look at any brushes with blends and try to reduce the number of steps (you may have to do some re-drawing) to what's necessary, i.e. from 255 to 50 and it may still look smooth.
Generally be on the lookout for having more elements or attributes in use than necessary.
When you get done, click and drag the brush back to the palette. If you want to make it a new brush, simply drop it anywhere in the brush preview window, and a dialog pops up. If you want to keep the brush under its original name, drag the rectified brush over the preview of the original, and alt-drop to re-write.
HTH
Bert
Bert Philippus -