There is nothing substancial in terms of performance that the quadcores have over the core2duos. They are quite expensive right now and not worth the money if you ask me.
However, DDR2 memory is cheap as hell. Stock up.
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I'm with Stu on this one, it totally depends on what you're using them for. There are some applications that will benefit considerably from having extra cores, like virtualization or compute intensive tasks. Other applications (like a file server) aren't going to see any noticeable improvement.
Prices on quad core Xeons aren't much higher than they are on dual core Woodcrest Xeons, especially when you consider their cost in relation to the overall cost of a server. If you can get a useable performance bump then they make sense.
I'm not sure where Core 2 Duo comes into the conversation since we're talking about server CPUs, not desktops.
It's worth noting that some time in the very near future, current Intel processor prices (at least on desktop processors - not totally sure about server cpus) will be dropping considerably. It looks like that time will be sometime in June, or July at the latest. So, if you do decide to upgrade, I'd say wait a couple weeks or a month if you can, and you'll be able to save a little extra (in relation to server total costs - a lot in relation to the processor cost itself).
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"If to err is human, then I must be some kind of human!" -Me
I would think that Citrix would be one case where you could benefit from more cores. Since it's basically a terminal server, it will be using the resources of the server to execute the applications. Even if you only have 3 or 4 users running Citrix apps simultaneously, they would probably see some improvement. You're probably only looking at a 10-12% price difference to go with quads.
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