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Actually my requirement is I want to design top-level form, after booting the system this form will display & ask for the user name & password. When user enter valid name & password after that he can work on the system otherwise it restrict the user. So when my form will display during these time I want disable C-A-T & ALT+Tab combination.
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It seems to me you are trying to re-write the Windows GINA without realising it. Why go to all the trouble when MS have provided a (relatively) secure and tested mechanism for this.
Why not create either a domian wide or local security group and check whether the logged on user is a memeber of that group. You can allow/deny access to your system on that basis
Take Care
Matt
If at first you don't succeed, skydiving is not for you.