The PIX has a problem with ftp over ssl. The pix does a fixup on the IP and port to allow the traffic through NAT/PAT. With ftp over ssl, the data channel is encrypted (including the TCP/IP headers) so the PIX can't read what's inside and can't do the fixup. The connection is basically trying to get to the internal IP address/negotioated port of the FTP server, not the public IP/translated port that the PIX will change as it passes through.
You can disable the ftp fixup, but then either passive or active ftp will fail (I forget which off the top of my head.). I suppose you could make some NAT exemption, but I haven't seen anything work yet.
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