I'm assuming that you're trying to prevent users from using the workbook if the macro's are not enabled.
The only way to accomplish this, is by creating an extra sheet, maybe with a single message on it, that they need to enable in order for the workbook to be useable, and hide all the sheets expect that one, then set workbook protection.
You will need to use VBA to accomplish this. If you search in the VBA forum,
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