If you don't put self as msExchaMasterAccountSID (the attribute that maps to the associated external account - they're the same thing. I prefer to use the name of the attribute msexchMasterAccountSID). If you don't set the attribute, then mail bounces and a 9548 is logged. The proper disposition is to disable the account and set the attribute until such time as you delete the account.
If you don't need access to the mail, and don't want NDRs, strip the smtp account from the user and give it to a DG with no members.
If you don't want the mail and do want it to NDR, just remove the smtp address from the user.
If you do want the mail, strip the smtp address from the user and add it to another mail enabled object (user or PF) where you want the mail to be delivered. Assign the party responsible for reviewing the mail appropriate permissions to the mail enabled object.