For standard computer stuff? Just a standard VGA HD15 cable, like on a monitor. If you wanted to play bluray or any type of hdcp content you would need hdmi, and the video card of the computer would need hdmi also. In the case of the VGA, yes you would need to have seperate audio, usually headphone to RCA jacks does the trick. If you wanted to go HDMI, it has the ability to carry the audio signal to the tv, as long as you have at least an ATI/AMD 4xxx and up, or newer nvidia GT420 and newer. I use an older ATI 4670 that I bought open box from Newegg for less than $60 a few years ago. This allows me to use hdmi for both audio and video, a bluray/dvd combo drive, and a Ceton quad tuner with cable card from comcast to use a computer to watch and record tv, and not have a cable box in my living room.