Control PC with remote device

[Beez123]

I have an application that waits for the user to hit a key combination (e.g. control followed by 1-2-3) and then produces an action. I want to know if there is a way to simulate this keypress without being at the keyboard. For instance, if a computer running the software was across the room or behind a door or something, is there a way to use an infared/bluetooth/etc. device so you could click a button on a remote and the PC would recognize the signal and simulate pressing control 123?

Thanks