Actually, you can move the database and media pool to new location.
First, go into job and save it off as an .asx script file through the save option, this allows you to quickly replug the job back in and makes it think it is not a new job, so the old database and media pools files will be reused.
Then copy the 00000.qsd folder and Database folder to an archived location. The qsd folder holds the job que and the database folder has all the databases.
Uninstall the old location, reinstall into new location.
Patch and what-not you need to do, then go into backup manager and select open, and point to job script files.
Once jobs are reloaded, cycled down all services, copy the qsd and database folders back into the new default locations, recycle the services to reread the database and media pools. Should be fine... done it a few times myself.. CA said it couldn't be done, but it is doable.