ISDN (Integrated Services Digital Network) or It Still Does Nothing...
Was and probably still is the benchmark for audio over distance for radio stations.
Depending on your territory you had 56K or 64K per channel, you could bond at least 2 channels and it gave perfectly clear audio. The associated data was sent over a separate 9K data channel.
Under set adapters could also be used on proprietary phones to achieve this if no direct ISDN was available.
However we are moving away from Circuit Switched to Packet Switched connections.
You can keep Circuit Switched ISDN but it will become more redundant as time goes on and more expensive.
Packet Switched connections are now Voice over Internet Protocol (VoIP)
This mostly means SIP - Session Initiated Protocol
For you it will mean reading up on Codecs - the digital encoding and decoding of the audio.
Different codecs will give different audio quality.
G703 & GSM would be examples of codecs.
Jitter - just like noise on older circuits.
Bandwidth - not always guaranteed unlike ISDN
Packet Prioritization - Adding a 'header packet' to outgoing voice packets to enable it to transverse the network quickly.
(End users will wait for an email but can not wait for time urgent voice packets)
Signalling Prioritization - Contacting a distant location needs to be prioritized before emails etc. but after voice packets.
Most telephone audio is now packet switched, the only circuit switched really is the telephone line from your premises still running on the now very old 50V DC.
If we were to install a telephone network today it would be a bus between buildings.
After the telephone exchanges our voice packets are transferred into mostly glass fiber to be sent to the destination...