You can supply criteria to a query by the value selected in the combo box. For example, let's say you have a table of addresses. The table has address, city, state, and zip fields. You want to be able to select by state. Set a combo box and use a query to supply the RowSource of the combo box with a list of states. The user selects a state in the combo box. In the AfterUpdate event of the combo box run a query that uses the value selected as criteria.
On the criteria line of the query design grid in the state field place the address of the combo box, like this:
Forms!FormName!ComboBoxName
The query will then look to the combo box and deliver just the records that match the value in the combo box.
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Uncle Jack