I had the same thing happen about a year ago (on an XP machine).
I was never able to figure out why it happened, but when I switched from Norton Internet Security to Trend Micro, my sound icon re-appeared in the systray. I had been using NIS for years before that, I guess some update had...
I've followed the instructions from this site on multiple computers and it worked perfectly:
http://www.askdavetaylor.com/how_can_i_fully_remove_norton_antivirus_from_my_system.html
Good luck
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